RESISTANCE IS NOT FUTILE: THE ROLE OF QUORUM SENSING PLASTICITY IN PSEUDOMONAS AERUGINOSA INFECTIONS AND ITS LINK TO INTRINSIC MECHANISMS OF ANTIBIOTIC RESISTANCE

Resistance Is Not Futile: The Role of Quorum Sensing Plasticity in Pseudomonas aeruginosa Infections and Its Link to Intrinsic Mechanisms of Antibiotic Resistance

Bacteria use a cell-cell communication process called quorum sensing (QS) to orchestrate collective behaviors.QS relies on the group-wide detection of extracellular signal molecules called autoinducers (AI).Quorum sensing is required for virulence and biofilm formation in the human pathogen Pseudomonas aeruginosa.In copyright Adjustable Rear Arm P.

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Transcriptome analysis of skin fibroblasts with dominant negative COL3A1 mutations provides molecular insights into the etiopathology of vascular Ehlers-Danlos syndrome.

Vascular Ehlers-Danlos syndrome (vEDS) is a dominantly inherited connective tissue disorder caused by mutations in the COL3A1 gene that encodes type III collagen (COLLIII), which is the major expressed collagen in blood vessels and hollow organs.The majority of disease-causing variants in COL3A1 are glycine substitutions and in-frame splice mutatio

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Rhythmic Components in Extracranial Brain Signals Reveal Multifaceted Task Modulation of Overlapping Neuronal Activity.

Oscillatory neuronal activity is implicated in many cognitive functions, and its phase coupling between sensors may reflect networks of communicating neuronal populations.Oscillatory activity is often studied using extracranial recordings and compared between experimental conditions.This is challenging, because there is overlap between sensor-level

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